Amazon.com: Pre Seed Fertility Lubricant, For Use by Couples Trying to Conceive : Health & Household When trying to conceive, choosing the right lubricant matters. Some common products like oil based lubricants, petroleum jelly, saliva, and regular lubricants may harm sperm and reduce fertility chances. Instead, opt for fertility friendly, Conceive Plus Fertility Lubricant: Can It Help Me Get Pregnant? twoplus Fertility blog Not all lubricants are created equal when it comes to fertility. Most commercial lubes (like K Y Jelly, Astroglide, Replens, Optilube, and even olive oil or saliva) can impair sperm motility or damage