Accutane Survival Tips (Derm Edition) Accutane aka isotretinoin is an oral retinoid used to treat severe, stubborn acne. As a BC dermatologist, here's what I tell my patients to make their Accutane shrinks oil glands but extreme dryness and irritation dont have to be part of the experience. Do this Use a gentle, non foaming cleanser Hydrate with lightweight, water based serums Amazon.com: Waterbased Lube 3.38 Fl Oz. Personal Lubricant w Aloe & Vitamin E, Portable, Hypoallergenic, Free of Paraben&Glycerin&PEGs, PH Balanced, Natural Smooth Slippery Glide Gel for Couples, Men, Women : Health & Household Accutane Products: The 7 Products That Saved My Skin When I Was on Isotretinoin SELF