Can You Use Silicone Lube with Condoms? Trojan ENZ Condoms, 3 ct Ralphs Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex Self lubricating condoms, explained Vox
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