Sometimes when people vape for the first time they can feel quite unwell and, in some cases, they can actually be sick. This is due to the nicotine they're ingesting and is Exclusive: Nicotine like chemicals in U.S. vapes may be more potent than nicotine, FDA says Reuters Notes from the Field: E Cigarette and Nicotine Pouch Use Among Middle and High School Students United States, 2024 MMWR Disposable e cigarettes and their nicotine delivery, usage pattern, and subjective effects in occasionally smoking adults Scientific Reports