Frontiers Inhalation of nicotine containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in ENaC overexpressing mice Association of electronic cigarette use and risk of COPD: a systematic review and meta analysis npj Primary Care Respiratory Medicine The evidence is clear: Young E cigarette users suffer from respiratory symptoms American Lung Association Cigarette smoke can reprogram cells in your airways, causing COPD to hang on after smoking ends